方法一：

import codecs

with codecs.open('somefile.txt', 'r', 'GBK') as f:
    data = f.read()
    print data

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方法二：

import sys
reload(sys)
sys.setdefaultencoding("utf-8")

fin = open('somefile.txt', 'r')
for eachLine in fin:
    line = eachLine.strip().decode('gbk', 'utf-8')
    print line