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脑细胞类型基础划分

脑细胞类型基础划分

作者: 倪桦 | 来源:发表于2022-05-14 22:28 被阅读0次

    Mice Brain Cell Markers
    推荐两个网站:
    CellMarker:http://biocc.hrbmu.edu.cn/CellMarker/
    panglaodb:https://panglaodb.se/index.html

    Cerebellum小脑

    ref_paper https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6788728

    genes_GP = c("Atoh1")#Granule precursors
    genes_GC = c("Nhlh1","Reln","Rbfox3")#Granule cells
    genes_Ac = c("Aldoc","Aqp4")#Astrocytes
    genes_Oc = c("S100b","Olig1")#Oligodendrocytes
    genes_PC = c("Gad1","Calb1","Pcp2")#Purkinje cells
    genes_EC = c("Pdgfrb","Pecam1")#Endothelial cells
    genes_Ic = c("Pax2")#Interneurons
    genes_Mc = c("Aldoc","Aqp4")#Microglia
    genes_IC = c("Ptprc","C1qa", "H2-Eb1","Cd14")#immune cells
    genes_FC = c("Ddr2","Tcf21","Col3a1","Col1a2","Col1a1")  #fibroblasts
    

    Cerebral cortex皮层

    genes_1 = c("Cx3cr1", "P2ry12", "Tmem119")#Microglia and non-parenchymal macrophages
    genes_2 = c("Cd163")#nonparenchymal macrophages
    genes_3 = c("Pdgfra", "Susd5","Cspg4")#oligodendrocyte lineage cells
    genes_4 = c("Mog", "Mag", "Gjc2")#mature myelinating oligodendrocytes 
    genes_5 = c("Pecam1", "Cldn5")#pan-endothelial cells 
    genes_6 = c("Slco1c1", "Ocln")#blood-brain barrier 
    genes_7 = c("Aldh1l1", "Slc1a3", "Aqp4")#astrocyte 
    genes_8 = c("Gdf10", "Vim", "Nbl1", "A2m")#Bergman glia
    genes_10 = c("Slc17a7", "Neurod6", "Mab21l1")#excitatory neurons 
    genes_11 = c('Gad1', "Reln", "Calb1")#inhibitory neurons
    genes_12 = c("Dcx", "Dlx2", "Ascl1", "Hes5")#neuroprogenitor cells 
    genes_13 = c("Des", "Mcam", "Pdgfrb")#pericytes 
    genes_14 = c('Bmx', "Jag1", "Efnb2")#arterioles
    genes_15 = c("Nr2f2", 'Flt4', "Vwf") #post-capillary venules
    genes_16 = c("Tfrc", "Car4", "Slc16a1")#capillaries 
    genes_17 = c("Jag1", "Notch1", "Hey1", "Vegfc", "Edn1", "Tmem100")#pro-angiogenic arterioles
    genes_18 = c (" Vcam1", "Icam1", "Lcn2","Hif1a", "Vwf", "Csf1")#post-capillary venules and capillaries enriched with inflammatory genes
    genes_IC = c("Ptprc", "H2-Eb1","Cd14")#immune cells
    

    参考博客 https://blog.csdn.net/zengwanqin/article/details/115964144

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