Doxercalciferol-D3

"目录号: HY-15285

Vitamin D Related-

Doxercalciferol-D3是Doxercalciferol的氘化形式，是维生素D2类似物，能作为维生素D受体活化剂。

VD/VDR

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生物活性

Description

Doxercalciferol-D3 is the deuterated form of Doxercalciferol, which is a Vitamin D2 analog that acts as a vitamin D receptor activator (VDRA).

References

[1].Brown AJ, Ritter CS, Knutson JC, Strugnell SA.  The vitamin D prodrugs 1alpha(OH)D2, 1alpha(OH)D3 and BCI-210 suppress PTH secretion by bovine parathyroid cells.  Nephrol Dial Transplant. 2006 Mar;21(3):644-50.

[2].Noonan W, Koch K, Nakane M, Ma J, Dixon D, Bolin A, Reinhart G.  Differential effects of vitamin D receptor activators on aortic calcification and pulse wave velocity in uraemic rats.  Nephrol Dial Transplant. 2008 Dec;23(12):3824-30.

[3].Sj?dén G.  Effects of vitamin D. A comparison of 1 alpha OHD2 and 1 alpha OHD3 in rats.  Acta Orthop Scand Suppl. 1985;217:1-84.