回文结构及TATA box 2020-11-25

AT/TA #最简单的回文序列2
CG/GC #最简单的回文序列2
AATT/TTAA/TATA/ATAT #简单回文序列4
GGCC/CCGG/GCGC/CGCG #简单回文序列4
GATC/CATG/GTAC/AGCT/TGCA/ACGT #简单的回文序列6
GGATCC/CCATGG/CCTAGG/GGTACC/AGGCCT/ACCGGT/TGGCCA/TCCGGA #衍生8
GAATTC/CAATTG/GTTAAC/CTTAAG/AAGCTT/AACGTT/TTGCAA/TTCGAA #再变换8

回文结构.png

参见：
https://en.wikibooks.org/wiki/Structural_Biochemistry/Nucleic_Acid/DNA/Palindromic_Sequencing

TAT box.png

RNA polymerase II accurately transcribes because of the TATA box’s directions. TATA box is the core promoter’s predominant DNA element. TATA-binding protein is what recognizes the TATA box. TATA-binding protein is found to have strong preferences for the TATA, shown through structural experiments and in vitro binding. Severe DNA bending is also induced by the TATA-binding protein. NC2 and Mot1p regulate the TATA-binding protein turnover at TATA boxes. It is proposed that the TATA-binding protein acts with NC2 and Mot1p to bend TATA and releases the TATA-binding protein at a more rapid pace from promoters of TATA. This occurs in vivo.
参见：
https://en.wikibooks.org/wiki/Structural_Biochemistry/TATA-Binding_Protein

TATA盒.png

参见：
https://zh.wikipedia.org/zh-cn/TATA盒