领域牛人:邓宏魁
工作经历:
1995-1997 美国纽约大学医学中心Skirball Institute,博士后研究
1998-2000 美国麻省ViaCell 公司,分子生物学主任
2001-至今 北京大学,特聘教授
2011-至今 北大-清华生命科学中心,高级研究员
2013-至今 北京大学干细胞研究中心主任,北京大学基础医学院细胞生物系主任
研究方向:胚胎干细胞的定向诱导分化。肝细胞的分化。
领域:周家喜
中国医学科学院北京协和医学院附属血液病医院血液病研究所,实验血液学国家重点实验室,国家血液病临床研究中心,天津300020;中国科学院干细胞医学中心,中国农业大学干细胞与再生医学系,天津300020电子地址:zhoujx@ihcams.ac.cn
Wang H, He J, Xu C, et al. Decoding Human Megakaryocyte Development. Cell Stem Cell. 2021;28(3):535-549.e8. doi:10.1016/j.stem.2020.11.006
Wang Y, Wang H, Guo J, et al. LGR4, Not LGR5, Enhances hPSC Hematopoiesis by Facilitating Mesoderm Induction via TGF-Beta Signaling Activation. Cell Rep. 2020;31(5):107600. doi:10.1016/j.celrep.2020.107600
Wang H, Wang M, Wang Y, et al. MSX2 suppression through inhibition of TGFβ signaling enhances hematopoietic differentiation of human embryonic stem cells [published correction appears in Stem Cell Res Ther. 2020 Jun 17;11(1):242]. Stem Cell Res Ther. 2020;11(1):147. Published 2020 Apr 5. doi:10.1186/s13287-020-01653-3
陈涛
中国医学科学院北京协和医学院附属血液病医院血液病研究所,实验血液学国家重点实验室,国家血液病临床研究中心,天津300020;中国科学院干细胞医学中心,中国农业大学干细胞与再生医学系,天津
Zhu C, Lian Y, Wang C, et al. Single-cell transcriptomics dissects hematopoietic cell destruction and T-cell engagement in aplastic anemia. Blood. 2021;138(1):23-33. doi:10.1182/blood.2020008966
Hu L, Yin X, Zhang Y, et al. Radiation-induced bystander effects impair transplanted human hematopoietic stem cells via oxidative DNA damage. Blood. 2021;137(24):3339-3350. doi:10.1182/blood.2020007362
Wang N, Yin J, You N, et al. TWIST1 preserves hematopoietic stem cell function via the CACNA1B/Ca2+/mitochondria axis. Blood. 2021;137(21):2907-2919. doi:10.1182/blood.2020007489
Huang D, Sun G, Hao X, et al. ANGPTL2-containing small extracellular vesicles from vascular endothelial cells accelerate leukemia progression. J Clin Invest. 2021;131(1):e138986. doi:10.1172/JCI138986
Wang Y, Wang H, Guo J, et al. LGR4, Not LGR5, Enhances hPSC Hematopoiesis by Facilitating Mesoderm Induction via TGF-Beta Signaling Activation. Cell Rep. 2020;31(5):107600. doi:10.1016/j.celrep.2020.107600
领域:koji Eto
领域:裴雪涛
Zhang B, Wu X, Zi G, et al. Large-scale generation of megakaryocytes from human embryonic stem cells using transgene-free and stepwise defined suspension culture conditions. Cell Prolif. 2021;54(4):e13002. doi:10.1111/cpr.13002
Qin J, Zhang J, Jiang J, et al. Direct chemical reprogramming of human cord blood erythroblasts to induced megakaryocytes that produce platelets. Cell Stem Cell. 2022;29(8):1229-1245.e7. doi:10.1016/j.stem.2022.07.004
Qu M, Zou X, Fang F, et al. Platelet-derived microparticles enhance megakaryocyte differentiation and platelet generation via miR-1915-3p. Nat Commun. 2020;11(1):4964. Published 2020 Oct 2. doi:10.1038/s41467-020-18802-0
Han Y, Ren J, Bai Y, Pei X, Han Y. Exosomes from hypoxia-treated human adipose-derived mesenchymal stem cells enhance angiogenesis through VEGF/VEGF-R [published correction appears in Int J Biochem Cell Biol. 2020 Sep;126:105805]. Int J Biochem Cell Biol. 2019;109:59-68. doi:10.1016/j.biocel.2019.01.017
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