氨基酸梨花性质
| 缩写 | 分子量 | 残基侧链体积 | 亲水性 | 极性 | 质子供体或受体 | 电性 | 物理化学 | 化学 | 体积 | 解离系数 | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Abbr | Molecular Weight | Residue Weight(-H2O) | Hydropathy | Polarity | Hydrogen donor or acceptor | Charge | Physicochemical | chemical | Volume | pKa1 | pKb2 | pKx3 | pl4 | |
| Ala | A | 89.1 | 71.08 | 1.8 | nonpolar | none | uncharged | aliphatic | aliphatic | 88.6 | 2.34 | 9.69 | – | 6 |
| Cys | C | 121.16 | 103.15 | 2.5 | nonpolar | none | uncharged | sulfur | sulfur | 108.5 | 1.96 | 10.28 | 8.18 | 5.07 |
| Asp | D | 133.11 | 115.09 | -3.5 | polar | acceptor | negative charged | acidic | acidic | 111.1 | 1.88 | 9.6 | 3.65 | 2.77 |
| Glu | E | 147.13 | 129.12 | -3.5 | polar | acceptor | negative charged | acidic | acidic | 138.4 | 2.19 | 9.67 | 4.25 | 3.22 |
| Phe | F | 165.19 | 147.18 | 2.8 | nonpolar | none | uncharged | F | aromatic | 189.9 | 1.83 | 9.13 | – | 5.48 |
| Gly | G | 75.07 | 57.05 | -0.4 | nonpolar | none | uncharged | G | aliphatic | 60.1 | 2.34 | 9.6 | – | 5.97 |
| His | H | 155.16 | 137.14 | -3.2 | polar | donor and acceptor | positive charged | basic | basic | 153.2 | 1.82 | 9.17 | 6 | 7.59 |
| Ile | I | 131.18 | 113.16 | 4.5 | nonpolar | none | uncharged | aliphatic | aliphatic | 166.7 | 2.36 | 9.6 | – | 6.02 |
| Lys | K | 146.19 | 128.18 | -3.9 | polar | donor | positive charged | basic | basic | 168.6 | 2.18 | 8.95 | 10.53 | 9.74 |
| Leu | L | 131.18 | 113.16 | 3.8 | nonpolar | none | uncharged | aliphatic | aliphatic | 166.7 | 2.36 | 9.6 | – | 5.98 |
| Met | M | 149.21 | 131.2 | 1.9 | nonpolar | none | uncharged | sulfur | sulfur | 162.9 | 2.28 | 9.21 | – | 5.74 |
| Asn | N | 132.12 | 114.11 | -3.5 | polar | donor and acceptor | uncharged | amide | amide | 114.1 | 2.02 | 8.8 | – | 5.41 |
| Pro | P | 115.13 | 97.12 | -1.6 | nonpolar | none | uncharged | P | aliphatic | 112.7 | 1.99 | 10.6 | – | 6.3 |
| Gln | Q | 146.15 | 128.13 | -3.5 | polar | donor and acceptor | uncharged | amide | amide | 143.8 | 2.17 | 9.13 | – | 5.65 |
| Arg | R | 174.2 | 156.19 | -4.5 | polar | donor | positive charged | basic | basic | 173.4 | 2.17 | 9.04 | 12.48 | 10.76 |
| Ser | S | 105.09 | 87.08 | -0.8 | polar | donor and acceptor | uncharged | hydroxyl | hydroxyl | 89 | 2.21 | 9.15 | – | 5.68 |
| Thr | T | 119.12 | 101.11 | -0.7 | polar | donor and acceptor | uncharged | hydroxyl | hydroxyl | 116.1 | 2.09 | 9.1 | – | 5.6 |
| Val | V | 117.15 | 99.13 | 4.2 | nonpolar | none | uncharged | aliphatic | aliphatic | 140 | 2.32 | 9.62 | – | 5.96 |
| Trp | W | 204.23 | 186.22 | -0.9 | nonpolar | donor | uncharged | W | aromatic | 227.8 | 2.83 | 9.39 | – | 5.89 |
| Tyr | Y | 181.19 | 163.18 | -1.3 | polar | donor and acceptor | uncharged | Y | aromatic | 193.6 | 2.2 | 9.11 | 10.07 | 5.66 |
参考：
[1] Pommié, C. et al., J. Mol. Recognit., 17, 17-32 (2004) PMID: 14872534, LIGM:284 pdf
[2] Kyte, J. and Doolittle, R.F., J. Mol. Biol., 157, 105-132 (1982).
[3] ApH 2 values: Normalized from Sereda et al., J. Chrom. 676: 139-153 (1994).
[4] BpH 7 values: Monera et al., J. Protein Sci. 1: 319-329 (1995).
http://www.imgt.org/IMGTeducation/Aide-memoire/_UK/aminoacids/IMGTclasses.html
https://www.sigmaaldrich.com/life-science/metabolomics/learning-center/amino-acid-reference-chart.html
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