美文网首页
GWAS名词

GWAS名词

作者: Wangxuann | 来源:发表于2020-06-06 08:55 被阅读0次

    Failure rate:The proportion of missing genotypes. Genotypes are classified as missing if the genotype-calling algorithm cannot infer the genotype with sufficient confidence. Can be calculated across each individual and/or SNP.

    False-negative/False-positive:假阴性/假阳性

    Genotype call rate:The proportion of genotypes per marker with non-missing data.

    Heterozygosity rate:The proportion of heterozygous genotypes for a given individual.

    Linkage Disequilibrium:Non-random association of alleles at two or more loci.

    Population substructure:The presence of distinct groups of individuals with subtle differences in allele frequency such that genetic data can be used to cluster these individuals into separate groups.

    Principal components analysis:A mathematical procedure for calculating a number of orthogonal latent variables that summarize a data matrix containing many potentially correlated variables.

    r2:A measure of the linkage disequilibrium (genetic correlation) between two markers. An r2 of 1 indicates that the two markers are perfectly correlated and an r2 of 0 indicates that the two markers are completely independent.

    相关文章

      网友评论

          本文标题:GWAS名词

          本文链接:https://www.haomeiwen.com/subject/lpwwzhtx.html