1. 安装Miniconda3的步骤

去官网下载安装文件：Miniconda — Conda中的MacOSX-x86_64-bit (bash installer)，可选择python3或python2.
```
wget -c -t o https://repo.anaconda.com/miniconda/Miniconda3-latest-MacOSX-x86_64.sh
```

下载后，可执行并安装：

chmod a+x Miniconda3-latest-MacOSX-x86_64.sh
./Miniconda3-latest-MacOSX-x86_64.sh

安装成功后，把路径写入bashrc或zshrc的环境变量中：
```
vi ~/.zshrc
export PATH="/Users/deng/miniconda3/bin:${PATH}"
```
然后输入source命令：
```
 source ~/.zshrc
```
检验是否安装成功：
```
conda list
```

显示大致以下命令表示安装成功：

  # packages in environment at /Users/deng/miniconda3:
  #
  # Name                    Version                   Build  Channel
  asn1crypto                0.24.0                   py37_0
  bzip2                     1.0.8                h1de35cc_0
  ca-certificates           2019.5.15                     0
  certifi                   2019.6.16                py37_0
  cffi                      1.12.3           py37hb5b8e2f_0
  chardet                   3.0.4                    py37_1
  conda                     4.7.10                   py37_0
  conda-package-handling    1.3.11                   py37_0
  cryptography              2.7              py37ha12b0ac_0
  idna                      2.8                      py37_0
  libarchive                3.3.3                h786848e_5
  libcxx                    4.0.1                hcfea43d_1
  libcxxabi                 4.0.1                hcfea43d_1
  libedit                   3.1.20181209         hb402a30_0
  libffi                    3.2.1                h475c297_4
  libiconv                  1.15                 hdd342a3_7
  libxml2                   2.9.9                hf6e021a_1
  lz4-c                     1.8.1.2              h1de35cc_0
  lzo                       2.10                 h362108e_2
  ncurses                   6.1                  h0a44026_1
  openssl                   1.1.1c               h1de35cc_1
  pip                       19.1.1                   py37_0
  pycosat                   0.6.3            py37h1de35cc_0
  pycparser                 2.19                     py37_0
  pyopenssl                 19.0.0                   py37_0
  pysocks                   1.7.0                    py37_0
  python                    3.7.3                h359304d_0
  python-libarchive-c       2.8                     py37_11
  python.app                2                        py37_9
  readline                  7.0                  h1de35cc_5
  requests                  2.22.0                   py37_0
  ruamel_yaml               0.15.46          py37h1de35cc_0
  setuptools                41.0.1                   py37_0
  six                       1.12.0                   py37_0
  sqlite                    3.29.0               ha441bb4_0
  tk                        8.6.8                ha441bb4_0
  tqdm                      4.32.1                     py_0
  urllib3                   1.24.2                   py37_0
  wheel                     0.33.4                   py37_0
  xz                        5.2.4                h1de35cc_4
  yaml                      0.1.7                hc338f04_2
  zlib                      1.2.11               h1de35cc_3
  zstd                      1.3.7                h5bba6e5_0

2. 安装Bioconda

添加channels：

  conda config --add channels conda-forge　　　
  conda config --add channels defaults　　　
  conda config --add channels r　　　
  conda config --add channels bioconda
  conda config --add channels https://mirrors.tuna.tsinghua.edu.cn/anaconda/pkgs/free/
  conda config --add channels https://mirrors.tuna.tsinghua.edu.cn/anaconda/cloud/conda-forge/
  conda config --add channels https://mirrors.tuna.tsinghua.edu.cn/anaconda/cloud/msys2/
  conda config --add channels https://mirrors.tuna.tsinghua.edu.cn/anaconda/cloud/bioconda/
  conda config --add channels https://mirrors.ustc.edu.cn/anaconda/pkgs/free/
  conda config --add channels https://mirrors.ustc.edu.cn/anaconda/cloud/bioconda/
  conda config --set show_channel_urls yes