在做肿瘤免疫相关性分析时,发现一个神奇的网站:TISIDB(an integrated repository portal for tumor-immune system interactions)

据说TISIDB整合了5大数据库,能进行10种分析和注释。

1.TISIDB探索
下面以CD96为例进行探索:


最重要的出场了,一共10种分析结果:

1.1 Immunotherapy
展示CD96基因与免疫治疗反应的关系,在单基因免疫分析中还是非常好用的。

1.2 Lymphocyte
分析28种TILs细胞与目标基因的相关性

1.3 Immunomodulator
免疫调节因子与目标基因相关性:Immunoinhibitor, immunostimulator, MHC molecule.
1.4 Chemokine
细胞因子和受体与目标基因


1.5 subtype
免疫亚型和分子亚型与目标基因

1.6 Clinical
临床特征,如OS, stage,grade与目标基因

可以看出TISIDB对于单基因泛癌免疫相关分析,还是非常友好的,下面就来看一下SCI论文是怎么应用的。
2.实战




参考链接:
A Comprehensive Bioinformatics Analysis of Notch Pathways in Bladder Cancer
网友评论