Annotationhub/Experimenthub报错问题：

> library(scRNAseq)
> fluidigm <- ReprocessedFluidigmData()
  |======================================================================| 100%

snapshotDate(): 2020-10-27
see ?scRNAseq and browseVignettes('scRNAseq') for documentation
Error: failed to load resource
  name: EH2569
  title: Fluidigm Tophat counts
  reason: Corrupt Cache: resource path
  See vignette section on corrupt cache
  cache: /Users/lhh/Library/Caches/ExperimentHub
  potential duplicate files: 
    1026d4db62c9e_2585
    c96e6bef9ca_2585

You will need to investigate the underlying BiocFileCache for the Hub and remove some or all of the files so that there is only a single entry for the resource path. Call the BiocFileCache constructor with the path listed as cache in the ERROR message.

> bfc <- BiocFileCache("/Users/lhh/Library/Caches/ExperimentHub")
> View(bfc)

Now we can query the BiocFileCache using the duplicate files of the ERROR message.

But when I do the query there is only one value

> res <- bfcquery(bfc, "2585", field="rpath", exact=FALSE)
Registered S3 method overwritten by 'cli':
  method     from    
  print.boxx spatstat
> res
# A tibble: 1 x 10
  rid   rname create_time access_time rpath rtype fpath last_modified_t… etag 
  <chr> <chr> <chr>       <chr>       <chr> <chr> <chr> <chr>            <chr>
1 BFC34 EH25… 2021-01-19… 2021-01-19… /Use… web   http… 2019-06-11 11:2… 2a9c…
# … with 1 more variable: expires <dbl>

The file path of the valid entry is

> bfcinfo(bfc, rid="BFC34") %>% dplyr::select(rpath)
# A tibble: 1 x 1
  rpath                                                          
  <chr>                                                          
1 /Users/lhh/Library/Caches/ExperimentHub/1026d4db62c9e_2585

Therefore the file c96e6bef9ca_2585 should be move or rename.

> library(ExperimentHub)
Loading required package: AnnotationHub

Attaching package: 'AnnotationHub'

The following object is masked from 'package:Biobase':

    cache

> ah = ExperimentHub()
> fl <- file.path(hubCache(ah), "c96e6bef9ca_2585")
> fl
[1] "/Users/lhh/Library/Caches/ExperimentHub/c96e6bef9ca_2585"
> unlink(fl)

参考：
https://bioconductor.org/packages/release/bioc/vignettes/AnnotationHub/inst/doc/TroubleshootingTheCache.html