1. 肾癌介绍
肾癌是一种常见的恶性肿瘤,位列癌症相关死亡率排名的前十位。肾癌有十余种亚型,主要包括肾细胞癌(renal
cell carcinoma,RCC,约占超过90%的肾癌)、移行细胞癌(transitional cell
carcinoma)、肾母细胞瘤(Wilms’
tumor)等。由于缺乏相关研究,人们对于肾癌的了解较少,其检测及治疗与其他癌种相比也较为困难。因此,解析复杂的肾癌组织内部成分有助于研究其发生机制、细胞类群及功能状态,具有重要的临床指导意义。
参考:https://zhuanlan.zhihu.com/p/65164387
2. 肾癌相关文章
Science,2018,Single-cell transcriptomes from human kidneys reveal the cellular identity of renal tumors,https://www.science.org/doi/10.1126/science.aat1699?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed,单细胞下载:EGA数据库
Cancer Cell, 2022,Mapping single-cell transcriptomes in the intra-tumoral and associated territories of kidney cancer, https://www.cell.com/cancer-cell/fulltext/S1535-6108(22)00548-7,单细胞下载:https://data.mendeley.com/datasets/g67bkbnhhg/1
nature immunology,2023,Exhausted intratumoral Vδ2− γδ T cells in human kidney cancer retain effector function,https://www.nature.com/articles/s41590-023-01448-7
3. 综述类文章
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