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SARI病毒疫情期间需要研究的科学问题

SARI病毒疫情期间需要研究的科学问题

作者: 瑚楊AFPMCC | 来源:发表于2020-02-01 09:38 被阅读0次

    Lipkin教授提出了针对新型冠状病毒感染的肺炎疫情防控关键的13问,如下:

    1.What is the strategy for identifying contactsof infected people?

    1.用什么方法确认与病毒感染者接触过的人员?

    2. What are the case definition criteria?

    2.确诊感染病例的定义标准是什么?

    3. What is the incubation period (mean, range)?How was it determined?

    3.病毒潜伏期是多少(平均值,范围)?如何确定的?

    4. What is the course of illness for mild,severe and fatal cases?

    4.轻症、重症和致死病例的病程各自情况如何?

    5. What is the time of onset and duration ofvirus shedding? How was this determined? Where is virus found: blood, saliva,sputum, feces?Who is tested for infection? How are theytested?Are the methods used for identifying cases,examining contacts, testing for virus and treatment consistent across sites inWuhan? In China?

    5.病毒的发作时间和传播过程需要的时间是多少?如何确定的?在哪里发现病毒:血液,唾液,痰,粪便?对哪些人进行了感染检测?如何检测他们?在武汉的各个站点之间用于识别病例,检查病人接触人员,测试病毒和治疗的方法是否一致?在全国范围内?

    6. What proportion of cases outside of Wuhan donot have Wuhan exposure?

    6.武汉地区以外无武汉接触史的病例比例是多少?

    7. What is the range of disease severity by age?

    7.按年龄划分疾病严重程度的范围是多少?

    8. What is the evidence to support the claim ofpre-symptomatic shedding?

    8.声称症状发作前的病毒散播有何支撑证据?

    9. What is the evidence of zoonotic exposure inpatients? What percentage went to animal markets?

    9.病人中因接触动物致病的证据是什么?病人中去过野生动物市场的比例是多少?

    10. What is the percentage of negative testresults?

    10.测试结果阴性的百分比是多少?

    11. What types of health care workers are athigh risk? At low risk? What percentage of health workers have become infected?

    11.哪些类型的医护人员处于感染高风险?低风险?被感染的医护人员的百分比是多少?

    12. Is there evidence of fomite transmission?

    12.是否有病媒传播的证据?

    13. Is there evidence of ‘super spreaders?

    13.是否有超级病毒传播者的证据?

    是否能回答这13个问题,正好验证我们在2003年以后建立的传染病防控体系的有效性。同时,在此次的会议中,中山大学陆家海团队与哥伦比亚大学的国际合作项目正式启动,将开展流行病学溯源、预测、诊断研

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