2023-05-15

The primary endpoint was the percentage of body weight loss (%BWL) at 1 year after surgery. Secondary endpoints were %BWL, serum albumin, hemoglobin, and lymphocyte count during 3 years after surgery, postoperative complica�tions, and overall survival (OS). Postoperative complications were graded according to the Clavien–Dindo classifcation of surgical complications, with events of grade II or higher considered to be complications. Refux esophagitis was confrmed by endoscopic examination at 1 year after surgery and assessed using the Los Angeles (LA) classifcation. Severe esophagitis was defned as grade C or D in the LA classifcation. Anastomotic stenosis was noted in any patient for whom the dilatation was performed by balloon because the endoscope could not pass through the esophago�gastric or esophagojejunal anastomosis.

主要终点是术后1年体重减轻的百分比(%BWL)。次要终点是术后3年BWL %、血清白蛋白、血红蛋白和淋巴细胞计数、术后并发症�和总生存期(OS)。术后并发症根据手术并发症的Clavien-Dindo分类进行分级，II级及以上的事件被认为是并发症。术后1年通过内窥镜检查确认返流性食管炎，并使用洛杉矶(LA)分类进行评估。重度食管炎在LA分级中定义为C级或D级。由于内镜不能通过食管�
胃或食管空肠吻合口，任何采用球囊扩张术的患者均出现吻合口狭窄。