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与bulk Rnaseq相比存在的问题:
- Amplification bias 扩增偏移
- Drop-out rates
- Transcriptional bursting
- Background noise
- Bias due to cell-cycle, cell size and other factors
- Often clear batch effects
一般流程
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Detecting duplicate/multiple cells
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本文标题:「scRNAseq」Quality Control of scR
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