「scRNAseq」Quality Control of scR

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与bulk Rnaseq相比存在的问题：

1. Amplification bias 扩增偏移
2. Drop-out rates
3. Transcriptional bursting
4. Background noise
5. Bias due to cell-cycle, cell size and other factors
6. Often clear batch effects

一般流程

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Detecting duplicate/multiple cells

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