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2018-12-17

2018-12-17

作者: whve | 来源:发表于2018-12-17 18:36 被阅读0次
    items AlzRisk polygenicpathways append
    Updated 24 January 2018 Last modified December 20, 2016
    Risk Factor Alcohol, B Vitamins, Blood Pressure, Cognitive Activity, Diabetes Mellitus, Dietary Pattern, Head injury, Homocysteine, Hormone Therapy, Inflammatory Biomarkers, Non-Steroidal Anti-Inflammatory Drugs, Nutritional Antioxidants, Obesity, Physical Activity, Statin use Bold part:the genes and risk factors can be related. Age, Aluminium, Aluminium antidote,anaemia, Head injury, occupational exposure, Organic solvent, Exposure to air pollution(Immune-system and related), A longer duration of being breastfed, Hypertension, low frequency magnetic fields, smoking, cancer (Cell cycle and DNA Repair), Atherosclerosis, etc.
    Environmental Infectious(4 places), Pathogens detected in the Alzheimer's disease brain, Dietary and lifestyle factors(7 places), Hormonal effects, Autoantibodies present in Alzheimer's disease sera, Epidemiological studies, Protective Drugs, Diets Vitamins and Vaccines(2 places), Biomarkers
    the genes and risk factors can be related Table 1: Components of the cholesterol shuttle and cholesterol and lipoprotein related genes that have been associated with Alzheimer's disease. Table 2. Growth factors and growth factor signalling. Table 3 Nuclear receptors and transcription factors associated with Alzheimer's disease. Table 4: Oxidative stress genes. Table 5: Proteases and protease inhibitors and activators associated with Alzheime's disease. Genes involved in glucose metabolism, acetyl CoA shuttling and acetylcholine metabolism associated with Alzheimer's disease. Cholinergic receptors. Table 7: Monoamine related genes associated with Alzheime's disease. Table 8 Immune-system and related. Table 9 Miscellaneous genes associated with Alzheimer's disease.
    items AlzGene append
    Updated 18 April 2011
    Studies 1395
    Genes 695
    Polymorphisms 2973
    Meta-analyses 320
    search Chromosome, Gene, Protein, Polymorphism, Study

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