背景：
Kitaake-1：野生型水稻
mRNA turnover
结果：
Rice bsr-k1 (broad-spectrum resistance Kitaake-1) mutant, which confersbroad-spectrum resistance against Magnaporthe oryzae and Xanthomonas oryzae pv oryzaewith no major penalty on key agronomic traits.
Bsr-k1 encodes a tetratricopeptiderepeats (TPRs)-containing protein, which binds to mRNAs of multiple OsPAL(OsPAL1–7) genes and promotes their turnover.
Loss of functionof the Bsr-k gene leads to accumulation of OsPAL1–7 mRNAs in the bsr-k1 mutant.
bsr-k1 produces a variant Os10g0548200 transcript with a 71-bp insertion derived from intron 8, causing a prematuretermination.
日积月累：
1.Crops carrying broad-spectrum resistance loci provide an effective strategy for controlling infectious disease because these loci typically confer resistance to diverse races of apathogen or even multiple species of pathogens.
2.Plant disease causes devastating yield losses in crop production, threatening global food security.
3. Repeatedover-application of pesticides to control plant diseases has polluted many environments around the globe.
4.Crop genetic improvement forresistance is the most economical and environmentally friendly approach topreventing disease outbreaks.
5. Insome cases, close linkage to undesirable agricultural traits has hindered theuse of broad-spectrum resistance genes to effectively control diseases of elitecultivars.
6. Thus,there is a need to identify novel genes conferring broad-spectrum resistance forintegration into crop genomes without penalizing major superior agriculturaltraits.
premature termination: 提前终止
strikingly：[ˈstraɪkɪŋli] adv.显著地，突出地，引人注目地
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