肿瘤临床NGS检测的意义

image.png

Opportunities for Genome Sequencing over a Patient’s Life time

• Predicting Future Risk of Cancer from the Germline Genome
• Epidemiology and Public Health
• Stratification for Intervention at Premalignant Stages
• Cancer Diagnosis
• Tumor Classification
• Predicting Patient Outcome
• Precision Cancer Treatment
• Cancer Monitoring

Biologic and Clinical Insights from Cancer Genomes

image.png

• Somatic Mutations That Drive Cancer
• Mutational Processes in Cancer
• Tumor History and Intratumor Heterogeneity
• Neoantigens in Cancer

Ref

1. Nangalia J, Campbell PJ. Genome Sequencing during a Patient's Journey through Cancer. N Engl J Med. 2019;381(22):2145-2156.