使用FuGePrior来对转录组数据查找融合基因
前面我们说到过,做融合基因分析的软件已经非常多了,但是2017年还是发了一个新工具,就是:FuGePrior: A novel gene fusion prioritization algorithm based on accurate fusion structure analysis in cancer RNA-seq samples , 可能是因为它主攻癌症转录组数据吧。软件主页是;https://philae.polito.it/paciello/FuGePrior/
跟deFuse工具比较:
ChimeraScan detected 55, 27, 197 and 132 fusions in MCF-7, KPL-4, BT-474 and SK-BR-3 cell lines, respectively.
Conversely, deFuse found 39, 42, 319 and 231 chimeric transcripts in the same cell lines.
未完待续
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