肺细胞类型markers

Feature plots of signature genes used to identify mouse lung cell populations

The following genes were used to identify general populations of cells:

• immune cells (Ptprc),
• epithelial cells (Epcam),
• endothelial cells (Pecam1, Lyve1, Vwf)
• mesenchymal cells (Col1a2).

The following genes were used to identify specific cell populations within the main types of cells:

• T cells (Cd3e),
• B cells (Cd19),
• myeloid cells (Fcgr1),
• neutrophils (Mmp9),
• type I pneumocytes (Akap5),
• type II pneumocytes (Sftpc),
• ciliated epithelial cells (Foxj1),
• club cells (Scgb1a1),
• lymphatic endothelial cells (Pecam1, Thy1),
• fibroblasts (Pdg fra)
• pericytes and smooth muscle cells (Acta2)
• mesothelial cells (Msln)
• platelets (Pf4)

Nature, 28 Oct 2020, 587(7834):466-471