![](https://img.haomeiwen.com/i6478923/806c38ce3274196e.png)
ABcompartment和TAD主要采用cworld 软件进行分析。
Cworld 软件架构如下:
![](https://img.haomeiwen.com/i6478923/9e95a6436e1792db.png)
![](https://img.haomeiwen.com/i6478923/f4652f94da7cc123.png)
Cworld软件安装
https://github.com/dekkerlab/cworld-dekker
![](https://img.haomeiwen.com/i6478923/38bc93b1d9857846.png)
安装cworld 需要安装以下包:
![](https://img.haomeiwen.com/i6478923/c54e86a28d70fd92.png)
步骤如下:
conda config --set always_yes yes --set changeps1 no
conda env create --name cworld --file cworld_environment.yml
conda clean --tarballs --index-cache --lock
source activate cworld
perl -MGD -e 'print $GD::VERSION ."\n";'
Cworld compartments 分析原理
![](https://img.haomeiwen.com/i6478923/5f7b8290734b95e7.png)
![](https://img.haomeiwen.com/i6478923/aaf23b636ab5d873.png)
Cworld compartments分析实例
![](https://img.haomeiwen.com/i6478923/14c1d687465fd248.png)
![](https://img.haomeiwen.com/i6478923/1d2b85124371ea67.png)
![](https://img.haomeiwen.com/i6478923/9c75c4d92b12414d.png)
使用实例:
![](https://img.haomeiwen.com/i6478923/a47b083e81d37ec2.png)
结果解读:
![](https://img.haomeiwen.com/i6478923/1392b01957c066bd.png)
![](https://img.haomeiwen.com/i6478923/7d53b2bcc43a83ec.png)
![](https://img.haomeiwen.com/i6478923/b699ef0c71d66e5a.png)
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